Expression of CatSper family transcripts in the mouse testis during post-natal development and human ejaculated spermatozoa: relationship to sperm motility
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چکیده
منابع مشابه
Dynamics of Notch Pathway Expression during Mouse Testis Post-Natal Development and along the Spermatogenic Cycle
The transcription and expression patterns of Notch pathway components (Notch 1-3, Delta1 and 4, Jagged1) and effectors (Hes1, Hes2, Hes5 and Nrarp) were evaluated (through RT-PCR and IHC) in the mouse testis at key moments of post-natal development, and along the adult spermatogenic cycle. Notch pathway components and effectors are transcribed in the testis and expressed in germ, Sertoli and Le...
متن کاملThe expression and significance of CATSPER1 in human testis and ejaculated spermatozoa.
AIM To investigate the distribution of cation channel of sperm 1 (CATSPER1) protein and the presence of CATSPER1 mRNA in human testis and ejaculated spermatozoa. The influence of anti-human CATSPER1 antibody upon human sperm motility was used to evaluate the function of human CATSPER1 and to estimate its possible use as a target for immunocontraception. METHODS Human ejaculated sperm from nor...
متن کاملThe CatSper channel modulates boar sperm motility during capacitation.
The cation channel of sperm (CatSper) comprises four transmembrane subunits specifically expressed in human, equine, murine and ovine spermatozoa, apparently implicated in capacitation, hyperactivation and acrosome exocytosis. Western blotting and immunocytochemistry showed hereby that CatSper subunits are also present in boar spermatozoa, primarily over the sperm neck, tail and cytoplasmic dro...
متن کاملAnalysis and significance of mRNA in human ejaculated sperm from normozoospermic donors: relationship to sperm motility and capacitation
S.Lambard, I.Galeraud-Denis, G.Martin, R.Levy, A.Chocat and S.Carreau UPRES EA 2608-USC INRA, University of Caen, Department of Genetics and Reproduction, CHRU Clemenceau, Caen 14032 and Laboratory of Reproductive Biology, Hopital Nord, 42055 Saint-Etienne, France To whom correspondence should be addressed at: UPRES EA 2608, USC INRA, Université IRBA, esplanade de la Paix, 14032 Caen cedex, Fra...
متن کاملeffects of vitamin-e treatment on catsper genes expression and sperm quality in the testis of the aging mouse
background: catsper genes are a novel family of four sperm-specific calcium channels, which indicate testis-specific expression patterns. despite the crucial role of catsper genes in the male reproduction, very little is known about the factors that regulate their expression. objective: the objective of this study was to investigate the effects of vitamin e treatment on the expression of catspe...
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ژورنال
عنوان ژورنال: MHR: Basic science of reproductive medicine
سال: 2007
ISSN: 1460-2407,1360-9947
DOI: 10.1093/molehr/gam009